Microfluidic methods used in exosome isolation

Exosomes are important biomarkers for clinical diagnosis. It is critical to isolate secreted exosomes from bodily fluids such as blood, saliva, breast milk, and urine liquid biopsy applications. The field of microfluidics provides numerous benefits biosample processing, diagnostics, prognostics. Several microfluidics-based methods have been employed the isolation purification in last ten years. These microfluidic can be grouped into two categories based on passive active mechanisms. In first group, inertial hydrodynamic forces separate their size differences. second external forcefields integrated platforms actively other bioparticles. this paper, application exosome discussed, future perspectives highlighted.